Common Side Effects_
Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.
Created By
Joseph Bennett, Steve Hely
Network
Adult Swim
Episodes
10
Updated Feb 16, 2026
WHERE TO WATCH
S
StackTV Amazon Channel
1 country
G
Global TV
FREE
1 country
DROPTHE_ GOSSIP
Overview
Common Side Effects has 2 seasons with 10 episodes spanning 2025-present.
Rating
With a 8.4/10 rating from 241 votes, Common Side Effects is considered highly rated.
Year context
Common Side Effects first aired 1 year ago in 2025.
CAST (5)
Dave King
Marshall Cuso (voice)
Emily Pendergast
Frances Applewhite (voice)
Mike Judge
Rick Kruger (voice)
Martha Kelly
Agent Harrington (voice)
Joseph Lee Anderson
Agent Copano (voice)
SEASONS (2 seasons, 10 episodes)
SEASON 1
01
Pilot
Marshall meets his old high school classmate Frances and lets her in on a world-changing secret.
02
Lakeshore Limited
Marshall's forced on the run as the DEA pursues him.
03
Hildy
Marshall visits an old mentor as new pressures mount.
04
Dumpsite
Frances tracks down Marshall in an unlikely location.
05
Star-Tel-Lite
Marshall, Frances, and their crazy neighbors deal with the aftermath of a dangerous incident.
06
In the System
Stuck in jail, Marshall faces new threats.
07
Blowfish
A chance encounter offers a risky opportunity for escape.
08
Amelia & Wyatt
Marshall and his new ally make a bold move.
09
Cliff's Edge
Marshall's mushroom project grows out of hand.
10
Raid
Dangerous forces converge on Marshall's camp.
SEASON 2
Episode details coming soon
SERIES INFO
2
Seasons
10
Episodes
23 min/ep
Per Episode
Returning Series
Status
CREW
Creator
Joseph Bennett
Creator
Steve Hely
Showrunner
Greg Daniels
NETWORKS (1)
Adult Swim
DETAILS
First Aired
Status
Returning Series
Seasons
2
Episodes
10
Episode Length
23 min/ep
Language
English
Country
Rating
8.4/10 (241 votes)
Popularity
7
IMDB
FREQUENTLY ASKED QUESTIONS
What is Common Side Effects about?
Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.
Where can I watch Common Side Effects?
Common Side Effects is available on Max, Adult Swim, YouTube TV, StackTV Amazon Channel, Global TV. Availability varies by region.
How many seasons does Common Side Effects have?
Common Side Effects has 2 seasons with 10 episodes total.
Who created Common Side Effects?
Common Side Effects was created by Joseph Bennett and Steve Hely.
Who stars in Common Side Effects?
The cast of Common Side Effects includes Dave King, Emily Pendergast, Mike Judge, Martha Kelly, Joseph Lee Anderson.
What is the rating of Common Side Effects?
Common Side Effects has a rating of 8.4 out of 10 based on 241 votes on TMDB.
Is Common Side Effects still running?
Common Side Effects is currently active with a status of "Returning Series."
GENRES (4)
Animation
Drama
Comedy
Sci-Fi & Fantasy