Love & Other Drugs_
"Addicted to one-night stands or dependent on one another?"
Maggie is an alluring free spirit who won't let anyone – or anything – tie her down. But she meets her match in Jamie, whose relentless and nearly infallible charm serves him well with the ladies and the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love.
Updated Feb 16, 2026
WHERE TO WATCH
DROPTHE_ GOSSIP
Box office
Love & Other Drugs earned $102.8M worldwide on a $30.0M budget — a 243% return on investment.
Year context
Love & Other Drugs was released 16 years ago in 2010.
CAST (20)
Jake Gyllenhaal
Jamie Randall
Anne Hathaway
Maggie Murdock
Oliver Platt
Bruce Winston
Hank Azaria
Dr. Stan Knight
Josh Gad
Josh Randall
Gabriel Macht
Trey Hannigan
Judy Greer
Cindy
Jill Clayburgh
Nancy Randall
George Segal
Dr. James Randall
Kate Jennings Grant
Gina
Katheryn Winnick
"Lisa"
Kimberly Scott
Gail
Peter Friedman
California Man
Nikki DeLoach
Christy
Natalie Gold
Dr. Helen Randall
Megan Ferguson
Farrah
Michael Benjamin Washington
Richard
Bingo O'Malley
Sam
Dorothy Silver
Sophie
LR
Lucy Roucis
UN Convention Parkinson's Speaker
CREW
BOX OFFICE
$30.0M
Budget
$102.8M
Revenue
+243%
ROI
BLOCKBUSTER
Verdict
STUDIOS (4)
DETAILS
Release
Status
Released
Runtime
112 min (1h 52m)
Language
English
Country
Rating
7.0/10 (5,490 votes)
Popularity
7
Budget
$30,000,000
Box Office
$102,800,000
Profit
+$72,800,000
IMDB
Trailer
FREQUENTLY ASKED QUESTIONS
What is Love & Other Drugs about?
Maggie is an alluring free spirit who won't let anyone – or anything – tie her down. But she meets her match in Jamie, whose relentless and nearly infallible charm serves him well with the ladies and the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love.
How long is Love & Other Drugs?
Love & Other Drugs has a runtime of 112 minutes (1h 52m).
Who directed Love & Other Drugs?
Love & Other Drugs was directed by Edward Zwick.
Who stars in Love & Other Drugs?
The cast of Love & Other Drugs includes Jake Gyllenhaal, Anne Hathaway, Oliver Platt, Hank Azaria, Josh Gad.
How much did Love & Other Drugs make at the box office?
Love & Other Drugs earned $102,800,000 worldwide at the box office. The production budget was $30,000,000.
What is the rating of Love & Other Drugs?
Love & Other Drugs has a rating of 7.0 out of 10 based on 5,490 votes on TMDB.
GENRES (3)
Drama
Comedy
Romance
KEYWORDS (5)
letter
sexual freedom
love
viagra
free spirit
Edward Zwick →